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Diablo Wiki
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Damage is the possible, but not guaranteed result of attacking from a monster to a player or vice versa. Damage can be realised by:

  • Melee damage. The attacker is toe-to-toe to the defender. Most weapons are melee weapons;
  • Ranged damage. There is a distance between the attacker and the defender. Bows and Crossbows are often used for ranged damage;
  • Spell damage. The attacker uses spells (from a Skill Tree) against the defender.

Spell damage is always successful. The success of melee end range damage depends from the Attack Rating.

In all case of damage the hitpoints of the defender is decreased. If the defender has no resistances, the hitpoints of the defender is decreased with the same amount as the damage from the attacker is. If the resistance is greater than 0, the amount of taken damage is decreased. If it is less than 0, the amount of taken damage is increased. If the damage is higher than the defender's hitpoints left, the defender dies.

There is a difference between Attacking and damaging. If you attack a monster, it is an attempt to do damage to it. It is not guaranteed that the attack is successful. In case of damage the attack was successful.

Character Attributes
Diablo I Diablo II Diablo III
StrengthDamageHealth Regeneration
DexterityAttack RatingDefenseBlock
VitalityLife
MagicManaMana Regeneration
Resistances
StrengthDamageHealth Regeneration
DexterityAttack RatingDefenseBlock
VitalityLifeStamina
EnergyManaMana Regeneration
Resistances
Strength — Armor, Barbarian Damage
Dexterity — Dodge, Demon Hunter & Monk Damage
Intelligence — All Resistances +0.1, Wizard & Witch Doctor Damage
VitalityLife
Armor •  Resistances
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